Female and Male Infertility

MAR prediction tools: KPIs, biological factors, RWE, and clinical decisions


Held on 10 May 2024

MAR prediction tools: KPIs, biological factors, RWE, and clinical decisions


10 May 2024


AI and Reproductive Health


Coming soon

MAR prediction tools: KPls, Biological factors, RWE, and clinical decisions

CME Live Webinar registration

Live Session:
10 May 2024

08.00  (BRT)
13.00 (CEST)
16.30 (IST)
21.00 (AEST)


These Virtual Workshop presentations aim to characterie measurable markers of success that work in real-world medically assisted reproduction (MAR) practice. They will also describe how clinicians can communicate effectively about key performance indicators (KPIs) to patients (who are often well-informed and data-literate but also need to know the individual relevance of population-level statistics). In addition, the presentations consider the evolving use of big data and AI in MAR, and will and evaluate the quality of real-world evidence relating to MAR treatment, focusing on recent studies that utilise large-scale registry datasets.

Globally, infertility rates are increasing, and birth rates are declining, because of concomitant socio-economic, physiological and environmental factors. When women present for infertility care in their mid- or late 30s there are clinical challenges for MAR providers, given that treatment protocols (and expectations) are typically established in populations of normoresponsive women aged ≤35 years. How do clinicians set realistic expectations and plan the optimal treatment course for women of advanced maternal age (AMA) who do not fit the profile of normoresponsive women? Understanding both global and local trends in fertility populations is important; treatment improvements centre on the relevance of statistical KPIs, but acknowledge that individual experiences of MAR will be personal and unique. The primary learning points from this webinar are for health professionals to understand how MAR populations are changing (globally and locally), and how and why approaches to treatment need to adapt to these changes. Such understanding affects treatment and procedural choices in MAR: breaking the data down into what matters most to the patient is extremely relevant to good clinical practice.

KPIs benchmark clinical practice at local, national and regional levels, especially in the era of ‘big data’ and information sharing. To be widely adopted in clinical settings, KPI must be measurable, reproducible and consistent, and look beyond live birth rates or even cumulative live birth rates:. However, MAR and AI or big data technologies are developing so rapidly that relevant clinical benchmarks, expectations, definitions and processes can be unclear in everyday practice. Indeed, information sharing in healthcare is behind the curve, compared with other sectors. Although some reasons for this are valid (relating to concerns about data protection, information security and sensitivity), data to be obtained for registries, for example, need to be sufficiently granular to drive powerful insights without compromising patient integrity or routine clinical practice (where not all data are obtained, cleaned and stored consistently).KPI should be defined for each treatment step and MAR milestone, to reduce bias as much as possible.

Certainly, traditional reliance on randomized study data is evolving andreal-world outcomes are often highly regarded in MAR.Exploring the value of real-world data is key for future clinical decision making.

Learning Objectives

After participating in this workshop and related activities, participants will be able to:

Target Audience

The program is intended for clinicians, embryologists, andrologists, scientists, and managers working in ART who wish to update their knowledge of advanced techniques and scientific innovations and understand best practices using evidence-based models of care.


The MAR Prediction Tools: KPls, Biological Factors, RWE, And Clinical Decisions, Virtual, Italy 10/05/2024 – 10/05/2024, has been accredited by the European Accreditation Council for Continuing Medical Education (EACCME©) with 3.0 European CME credits (ECMEC’s). Each medical specialist should claim only those hours of credit that he/she actually spent in the educational activity.

“Through an agreement between the Union Européenne des Médecins Spécialistes and the American Medical Association, physicians may convert EACCME’ credits to an equivalent number of AMA PRA Category 1 CreditsTM. Information on the process to convert EACCME© credit to AMA credit can be found at https•//edhub.ama-assn.org/pages/applications

Live educational activities, occurring outside of Canada, recognised by the UEMS-EACCME© for ECMEC’s are deemed to be Accredited Group Learning Activities (Section 1) as defined by the Maintenance of Certification Program of the Royal College of Physicians and Surgeons of Canada



Carlo Alviggi

Carlo Alviggi

Fertility Unit, University of Naples “Federico II”
Naples, Italy
Jérôme Chambost

Jérôme Chambost

Apricity Fertility
Paris, France


Carlo Alviggi

Carlo Alviggi

Fertility Unit, University of Naples “Federico II”
Naples, Italy
Jérôme Chambost

Jérôme Chambost

Apricity Fertility
Paris, France
Danilo Cimadomo

Danilo Cimadomo

University of Pavia
Pavia, Italy
Biljana Popovic-Todorovic

Biljana Popovic-Todorovic

Avala Hospital
Belgrade, Serbia

International Committee

Baris Ata

Baris Ata

ART Fertility Center
Koc University Istanbul
Dubai, United Arab Emirates
Alvaro Ceschin

Alvaro Ceschin

President of Brazilian Association of Assisted Reproduction (SBRA)
Brasilia, Brazil
Adriano Fregonesi

Adriano Fregonesi

Associate Professor Urology of State University of Campinas Brazil (UNICAMP) and Jundiai School of Medicine
Head of the Department of Urology / Andrology State University of Campinas Brazil
Delegate Sociedade Brasileira de Urologia São Paulo (SBU SP)
Joaquin Llácer

Joaquin Llácer

Madrid, Spain
Kevin McEleny

Kevin McEleny

Queen Elizabeth Hospital
Gateshead and the Freeman Hospital
Newcastle, UK
Habib Midassi

Habib Midassi

Polyclinique Ibn Annafis
Sfax, Tunisia
Paula Navarro

Paula Navarro

Ribeirão Preto Medical School
University of Sao Paulo,
Sao Paulo, Brazil
Amina Oumeziane

Amina Oumeziane

Tiziri IVF Center
Algiers, Algeria
Emre Pabuçcu

Emre Pabuçcu

Ufuk University School of Medicine
Ankara, Turkey



· Carlo Alviggi ·

Carlo Alviggi earned his MD degree in 1994, from the Faculty of Medicine of the University of Naples “Federico II” in Naples, Italy; he specialized in obstetrics and gynaecology in 1998, and gained a PhD in 2001, from the same university. During his career, he collaborated with: The Imperial College of London, in London, UK; the Laboratory of Immunology of the Italian National Research Council in Naples; and the Autoimmunity and Tolerance Laboratory of the University of California in Los Angeles, CA, USA. This network resulted in various publications, some of which concern new hypotheses on the pathogenesis of pelvic endometriosis. He is now an associate professor in reproductive medicine at the Fertility Unit of the University of Naples “Federico II”. Professor Alviggi’s current research interests are the role of luteinizing hormone (LH) in folliculogenesis; the use of LH-containing drugs in patients undergoing ovarian controlled stimulation for IVF; the pathogenesis of pelvic endometriosis; oncofertility; reproductive endicrinology and the genetics of human reproduction. He has participated in several national and international (phase 2 and 3) multicentric, prospective randomized trials. Professor Alviggi has published extensively and has been invited to lecture at over 200 international meetings dealing with reproductive medicine and gynaecological endocrinology; he is also starter and co-founder of the Poseidon group, an international collaborative network dedicated to low prognosis patients in Assisted Reproductive Technology and vice-President of the “Società Italiana di Fertilità e Sterilità – Medicina della Riproduzione”.

· Jérôme Chambost ·

Jerome Chambost received a Master of Engineering from Centrale Paris, France and a Master of Engineering Science and management from the University of Queensland, Australia with a strong focus on data science.

He worked for three years as a senior consultant and data scientist for Roland Bergerspecializing in big data and artificial intelligence projects for the healthcare and Life sciences industries.

He joined APRICITY in 2019 as head of AI to leverage artificial intelligence technologies and improve care, provide transparency and maximise chances of success for fertility treatments with a focus on stimulation and embryology.

He became Chief Data Officer of Apricity in 2021, in charge of accelerating the data transformation of the company and is since 2022 Chief Technology Officer of Apricity, in charge of the artificial intelligence and the technical team, with the goal to design personalize treatments algorithms an implement them in Apricity suite of services for the patients and medical staff.
APRICITY is a virtual fertility clinic. It aims, first, at disrupting the fertility treatment experience and then, at improving chances for women and couples who have difficulties to conceive leveraging data and artificial intelligence. The Apricity project is developed with leading global IVF experts and has been launched in the UK and in Spain to start with.


Jerome Chambost is also board member of Labelia Labs (formerly Substra Foundation) since 2020. Labelia Labs is a non-profit organization with the mission of developing the positive impacts of Data Science by equipping and promoting collaborative, responsible and trustworthy approaches.


· Danilo Cimadomo ·

Dr Cimadomo is Innovation in Embryology Director and Science and Research manager Italy of IVIRMA Global Research Alliance. He has authored >120 papers. He is Basic Science officer and Coordinator Elect of the ESHRE SIG Implantation and Early Pregnancy, Associate Editor of Human Reproduction and Section Editor in Clinical Embryology of Reproductive BioMedicine Online. He participated to the ESHRE working groups updating the GPRs for embryo biopsy, and for RIF management. He coordinates the Master “Biology and Biotechnology of Reproduction: from Research to Clinics” at the University of Pavia.

· Biljana Popovic Todorovic ·

Biljana Popovic Todorovic is a fertility specialist, head of IVF  at Avala hospital in Belgrade. She has worked for a number of years at the Centre for Reproductive Medicine, UZ Brussel in Belgium. Medical degree was obtained at Belgrade University School of Medicine and ob/gyn specialization from the Institute of Gynecology and Obstetrics in Belgrade, Clinical Centre of Serbia.  She obtained her PhD degree in 2004 at the Faculty of Health Sciences, University of Copenhagen on “Optimising rFSH dose regimens for in vitro fertilization”.  She is subspecialist in the field of Reproductive Medicine ESHRE/EBCOG and Clinical Andrologist (European Academy of Andrology), both achieved at the Centre for Reproductive Medicine, UZ Brussel, Belgium. Her clinical research activity is focused on reproductive endocrinology and clinical andrology.  Dr Popovic Todorovic is author of number of publications and book chapters and is a reviewer for several international journals in the field of Reproductive Medicine as well as the ESHRE clinical inspector for the certification of IVF centers and assessor for ESHRE/EBCOG accreditation for subspecialization in Reproductive Medicine. Dr Popovic Todorovic is the chair of the board of directors of Serbian Society for Reproductive Medicine. 

· Baris Ata ·

Baris Ata graduated from the Istanbul School of Medicine in 1998. He completed residency training in Obstetrics and Gynecology in 2003. During medical school and residency training he attended courses on research methodology, assisted reproduction and gynecological endoscopy around the world. His keen interest to improve his research skills led to acquisition of a Master’s Degree in Clinical Trials from the prestigious London School of Hygiene and of Tropical Medicine. He completed a three years long clinical and research fellowship program in Reproductive Gynecological Endocrinology and Infertility at McGill University, Montreal, Canada in 2011. Upon returning to Turkey he founded and assumed the directorship of the assisted reproduction unit of the Uludağ University, a highly successful program that grew to over 500 IVF cycles per annum in less than two years. He recently moved to Koç University. He has several awards of excellence as a resident, fellow, clinician and scholar. His research is on clinical aspects of female infertility including but not limited to ultrasound imaging of female reproductive tract, luteal phase physiology and support, prevention and management of ovarian hyperstimulation syndrome and in vitro maturation. Baris has over 100 publications on various aspects of assisted reproduction. He is sitting on the editorial board of six journals including Human Reproduction, and is a regular ad hoc reviewer for leading journals in his field. He is a member of the executive board of the Turkish Society of Reproductive Medicine and the board of directors of the International Society of In Vitro Fertilization.

· Alvaro Ceschin ·

Graduated in Medicine from the Federal University of Paraná (UFPR), in 1985.

Training in Human Reproduction at the Huntington Reproductive Center in Pasadena, California/USA, in 1991.

PhD in Principles of Surgery, in the area of concentration in Molecular Biology, from UFPR, completed in 2006, with the theme: “Comparative study of the viability of ovaries cryopreserved by slow freezing and vitrification – study in rats”.

Residency in Gynecology and Obstetrics at the Santa Brígida Hospital and Maternity Hospital, in Curitiba/PR, from 1987 to 1989.

Master’s degree in Principles of Surgery from the Research Institute of Faculdade Evangéilca do Paraná in 2002, with the theme: “Indirect hormonal assessment and study of follicular preservation in autologous ovarian tissue transplanted to the inguinal region, in rats”.

· Adriano Fregonesi ·

Free professor at the surgery department at UNICAMP. Assistant to the urology discipline at UNICAMP. Coordinator of the andrology sector of the urology discipline at UNICAMP.

· Joaquín Llacer ·

Dr. Llácer has over 30 years of experience in the field of assisted reproduction. He holds a Degree in Medicine and Surgery from the University of Valencia, specializing in obstetrics and gynecology at Hospital Universitario La Fe (Valencia) and holds a PhD in Medicine from the University Miguel Hernández of Elche. During the past 26 years Dr. Llácer has been part of the team of gynecologists at Instituto Bernabéu, where he also took part in the medical direction of the group and was a member of the Board of Directors.   

Among his professional achievements it was particularly noteworthy the extraordinary doctorate award for his thesis, as well has being awarded by the British Fertility Society and the American Society for Reproductive Medicine. In addition, Dr. Llácer has combined his medical activity with academic teaching in different master’s degree at University Complutense of Madrid and University of Alicante. He has authored over 50 papers in reproductive medicine journals, both national and international, and is currently a member of the scientific committee of the Spanish Fertility Society (SEF).

· Kevin McEleny ·

Mr Kevin McEleny is a Consultant Urologist working both in Newcastle and at the Queen Elizabeth Hospital in Gateshead since 2009.

He is also Consultant Andrologist and Clinical Lead for the male factor clinic at the Newcastle Fertility Centre, located at the International Centre for Life, Times Square, Newcastle upon Tyne.

After completing his medical training and PhD at University College, Dublin, he continued his urological training in the Northern Region prior to his consultant appointment.

His main clinical interests include treating and diagnosing men with fertility problems. He organised and delivers the supra-regional Male Fertility service.

His research interests are in the field of male fertility and he is actively involved in male fertility training nationally.

· Habib Midassi ·

Assistant professor of obstetrics and gynecology,Sfax university.Tunisia.(1987)

Mr Habib has completed his higher accreditation in Obstetrics and Gynecology in 1986

He works six years  as a consultant  in the Sfax teatching hospital .in 1988 he has his private office of gynecology and obstetrics.Since 2007 he also works in the IVF  center  of the polyclinic Ibn Annafis ,Sfax.Tunisia.

He has a wide experience in treating infertile couple with the first specialized fertility consultation in Tunisia (1984) .

Besides laparoscopic  Surgery, his professional interests include ovarian reserve ,luteal phase support and medical treatement of uterine fibroids

· Paula Andrea Navarro ·

Associate Professor at FMRP-USP (Human Reproduction Sector, Department of Gynecology and Obstetrics), President of the Scientific Integrity and Good Practices in Research Committee at FMRP-USP, Director of the Assisted Reproduction Laboratory, Deputy Coordinator of the Human Reproduction Center , Coordinator of the Postgraduate Program in Gynecology and Obstetrics at FMRP-USP, President of the Brazilian Society of Human Reproduction (SBRH, biennium 2023 to 2025), Member of the Technical Chamber of Assisted Reproduction of the Federal Council of Medicine and Member of the National Commission Specialist (CNE) of Assisted Reproduction of the Brazilian Federation of Gynecology and Obstetrics (FEBRASGO). Researcher at the National Institute of Sciences and Technology/CNPq – Hormones and Women’s Health, Ad Hoc consultant for FAPESP, CNPq and CAPES. Chief Editor of the Human Reproduction Archives, Associate Editor of Reproductive Sciences and the Brazilian Journal of Ginecology and Obstetrics, Member of the Editorial Board of the Journal of Assisted Reproduction and Genetics and Ad Hoc reviewer for several high-impact scientific journals. Graduated in Medicine from the Faculty of Medicine of Ribeirão Preto at the University of São Paulo (FMRP-USP; 1995), medical residency in Gynecology and Obstetrics at the Hospital das Clínicas de Ribeirão Preto (HCRP-USP; 1999); master’s degree (2000), Research Fellow in Reproductive Endocrinology and Infertility, Women and Infants Hospital, Brown University and Laboratory for Reproductive Medicine, Marine Biological Laboratory (2001-2002) and PhD (2003) in Health Sciences, Gynecology and Obstetrics, FMRP -USP. Post-doctorate at New York University (2016-2017). His main research interests include: Understanding the etiopathogenic mechanisms of endometriosis-related infertility and other infertility factors; Improving the efficiency of assisted reproduction techniques; Evaluate the efficiency and safety of new strategies (adds on) in assisted reproduction procedures; Improvement of fertility preservation strategies, especially oocyte freezing; Improving access to infertility treatment

· Amina Oumeziane ·

Dr Oumeziane has a Medical Degree from Medicine’s Faculty, Algiers in 1989 and Post Graduate Degree-Specialty in gynecology obstetrics from medicine’s faculty, Algiers in 1994.
Completed her training in reproductive medicine at Cochin hospital Assistance Publique Hôpitaux , Paris.
In 2000, received Academic Diploma of Investigation and Management of Infertility from Medicine’s Faculty Rene Descartes Paris, France in 2007 and Diploma in Basic of Reproductive Medicine and Embryology from International School of Medicine Kiel, Munich in 2012.
Head of Tiziri ivf center in Algiers since 2004.
Founder of of subspeciality certificate in infertility in 2019.
Amina Oumeziane is the founder of the Algerian Society of Reproductive Medicine (SAMERE), served as its First president from 2013 to 2016 and Scientific Director from 2016-until now.

Member of the American Society of Reproductive Medicine (ASRM) and European Society of Human reproduction and Embryology (ESHRE), Reviewer in global reproductive health IFFS journal, RBMO and MEFS journals Amina’s major interest areas: Luteal phase, Agonist triggering, Frozen strategy, poor responders .

· Emre Pabuçcu ·

Emre Göksan Pabuçcu was born in Ankara in 1981. After graduating from TED Ankara Private High School, he started his medical education in Ankara University Faculty of Medicine. He completed his residency program in the Department of Obstetrics and Gynecology, Ankara University Faculty of Medicine. He has been working at Ufuk University, Department of Obstetrics and Gynecology since 2013 where he received his Associated Professorship in 2017. He has worked at Houston Fertility Specialists Clinic and Texas Woman’s Hospital, Texas (2016) as an observer in the field of preimplantation genetic testing and minimal invasive surgery. He has also been working at Centrum Clinic Private IVF Center, Ankara/Turkey since 2012. He is actively interested in Reproductive Endocrinology and Reproductive Endoscopic procedures.  He is a former board member of International Society of Gynecologic Endoscopy (ISGE). Dr. Pabuçcu is currently a reviewer of several local and international journals about Reproductive Medicine, Endocrinology and Endoscopy. He has published more than 70 papers in peer reviewed journals. 

· Martin O. Savage ·

Martin Savage is Emeritus Professor of Paediatric Endocrinology at William Harvey Research Institute, Barts and the London School of Medicine & Dentistry, Queen Mary, University of London. He was head of the Paediatric Endocrine Unit at Barts and the London School of Medicine from 1982 to 2007. He has interests in growth disorders, specifically those with abnormalities in the GH-IGF-1 axis and in phenotype-genotype relationships of GH-IGF-1 axis defects, notably GH resistance. He published the first human case of an IGF-1 gene defect in the New England Journal of Medicine in 1996.  His other interests are Cushing’s syndrome and growth in chronic inflammatory diseases. He was General Secretary of the European Society for Paediatric Endocrinology (ESPE) from 1997 to 2004. He has lectured in 60 countries and has published 482 original articles, reviews, textbook chapters and books. In 2007, he was awarded the ESPE Andrea Prader Prize for contributions to paediatric endocrinology and in 2018 he received a Visionary Award from the American Human Growth Foundation. In 2022, he received a Research Excellence Award from the Dr Sulaiman Al Habib Medical Journal in Riyadh, and the British Society of Paediatric Endocrinology & Diabetes James M. Tanner Lifetime Achievement Award. He continues to lecture nationally and internationally.