Our educational activities are supported by an independent grant from the Healthcare business of Merck KGaA, Darmstadt, Germany; and additional support from FUJIFILM EUROPE GMBH, Fujifilm Italia S.p.A., FUJIFILM France S.A.S and S&R Farmaceutici Spa.
Overview
The role of luteinizing hormone (LH) during folliculogenesis has intrigued the scientific and medical community for at least three decades. There is an emerging galaxy of research to explore concerning this enigmatic subject. The availability of recombinant drugs now offers, for the first time, the opportunity to examine the role of follicle stimulating hormone and LH separately. An emerging topic during last year’s conference was LH supplementation to improve the outcome in a subgroup of low prognosis patients selected according to POSEIDON classification
During this conference we will discuss the management of these low prognosis patients in greater detail. Notably, we will move beyond controlled ovarian stimulation to explore further the involvement of LH in personalizing the luteal phase and in male infertility. Also, on the agenda will be the extra-gonadal effect of LH, including potential immune-modulation at the endometrium.
Following the precedent set at last year’s conference, considerable time will be devoted to basic science, alongside such controversial issues as progesterone rise and pharmacogenomics. This year we have attracted prominent scientists from the worlds of endocrinology, andrology, immunology and embryology to take part in our engaging educational programme.
Learning Objectives
- Understand the importance of luteinizing activity during folliculogenesis and beyond.
- Understand the dynamics of hypothalamic-pituitary axis in the pathogenesis of hypo- and normo-gonadotropic amenorrhea.
- Comprehend the concept of relative gonadotropin deficiency.
- Discuss and debate the management of low prognosis patients.
- Comprehend the clinical utility of LH supplementation to patients classified according to the POSEIDON criteria.
- Discover the clinical relevance of LH supplementation in ART.
- Analyse the relevance of LH during the luteal phase and introduce the concept of individualized luteal phase support.
- Explore the potential role of LH in male infertility treatment.
Target Audience
This programme is designed for clinicians and biologists working in assisted reproductive medicine, who want to acquire up-to date information to improve their current practice.
Accreditation
The accreditation is valid for the live event onsite as well as for the recorded live streaming for a period of 3 months after the conference.
The Third World Conference on Luteinizing Hormone in ART, Naples, Italy, 27/05/2022-28/05/2022 has been accredited by the European Accreditation Council for Continuing Medical Education (EACCME®) with 8 European CME credits (ECMEC®s). Each medical specialist should claim only those hours of credit that he/she actually spent in the educational activity.
Through an agreement between the Union Européenne des Médecins Spécialistes and the American Medical Association, physicians may convert EACCME® credits to an equivalent number of AMA PRA Category 1 CreditsTM. Information on the process to convert EACCME® credit to AMA credit can be found at www.ama-assn.org/education/earn-credit-participation-international-activities.
Live educational activities, occurring outside of Canada, recognised by the UEMS-EACCME® for ECMEC®s are deemed to be Accredited Group Learning Activities (Section 1) as defined by the Maintenance of Certification Program of the Royal College of Physicians and Surgeons of Canada.

The content of the following has been certified by the CPD Certification Service as conforming to continuing professional development principles, 3rd World Conference on Luteinizing Hormone in ART: Applying technologies, learning from nature. Event: 27th –28th May 2022

Free Educational resources
Enter our new E-Learning platform to access the educational materials.
You will be able to review the conference materials as well as watch the recorded streaming and get your CME certificate.
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3rd World Conference on Luteinizing Hormone in ART
Applying technologies,
learning from nature
Accreditation
Language
Chairs
Faculty
Federico II University
Naples, Italy
University of Saskatchewan
Saskatoon, Canada
IVRMA
Valencia, Spain
Centre for Gynaecological Endocrinology and Reproductive Medicine
Stuttgart, Germany
University of Modena and Reggio Emilia
Modena, Italy
Federico II University
Naples, Italy
Federico II University
Naples, Italy
Androfert – Andrology and Human Reproduction Clinic
Campinas, Brazil
Fertility Centre Hamburg
Hamburg, Germany
Fertility Clinic, Skive Regional Hospital
Faculty of Health, Aarhus University
Aarhus, Denmark
Saint Camillus International University Of Health Science
Rome, Italy
Department of Medical and Surgical Sciences for Children and Adults
Institute of Obstetrics and Gynecology Policlinico di Modena
University of Modena and Reggio Emilia
Modena, Italy
Federico II University
Naples, Italy
Tel-Aviv University
Tel-Aviv, Israel
Dexeus University Hospital
Barcelona, Spain
University of Ferrara
Ferrara, Italy
MATER PRIME – Reproductive Medicine
São Paulo, Brazil
University of Modena and Reggio Emilia
Modena, Italy
King’s College London
London, UK
GeneraLife, Centres for Reproductive Medicine
Rome, Italy
IVIRMA Madrid
Universidad Rey Juan Carlos
Madrid, Spain
Anatolia IVF and Women’s Health Center
Ankara, Turkey
Final Program
08:00 Registration
08.40 Med.E.A. – Medical Education Academy Welcome
R. Fischer, Germany
08.45 Conference welcome
C. Alviggi, Italy
08.50 Local welcome
Gaetano Manfredi (Mayor of Naples)
Matteo Lorito (Rector of Federico II University)
Giuseppe Bifulco (Director of the Maternal-Infant Health Department, University Hospital Federico II)
09.00 Introduction and objectives. Poll questions day 1
S. C. Esteves, Brazil; P. Humaidan, Denmark
09.10 Introductive lecture
The dialogue between endocrine and immune systems in human reproduction
Seeking for a perfect ecosystem
G. Matarese, Italy
Session I
A deep dive into Folliculogenesis
Chairs: F. M. Ubaldi, Italy – E. Bosch, Spain
09.30 L1 – New insights in follicular growth
Continuous flow or cyclic waves?
A. Bearwarld, Canada
09.50 L2 – LH throughout follicle life
From ocean depths to final undertow
A. La Marca, Italy
10.10 Discussion
10.30 Coffee break
Session II
Rays of light on impaired gonadotropins function
Chairs: M. Simoni, Italy – S. K. Sunkara, UK
10.50 L3 – FSH and LH deficiency
The sunrise of a new concept
C. Alviggi, Italy
11.10 L4 – LH in Hypothalamic amenorrhea and PCOS
The breeze and the windstorm
A. Colao, Italy
11.30 L5 – LH activity and male infertility
The eighth color in the rainbow
S. Esteves, Brazil
11.50 Discussion
Session III
LH in good prognosis women: Hiking through the mountains of literature
Chairs: P. Humaidan, Denmark – H. Yarali, Turkey
12.20 L6 – Defining the right indicators of efficacy
A steep mountain to climb
S. Sunkara, UK
12.40 L7 – State of the art according to EBM
What’s the view from the top?
M. Roque, Brazil
13.00 Discussion
13.20 Lunch
Session IV
LH in low prognosis patients: Seeking the balance in the forest
Chairs: R. Fischer, Germany – C. Alviggi, Italy
14.20 L8 – Capability of Bologna criteria to discriminate low prognosis patients
The original roots
H. Yarali, Turkey
14.40 L9 – Capability of Poseidon criteria to discriminate low prognosis patients
The growing tree
S. Esteves, Brazil
15.00 Coffree Break
15.20 L10 – LH in poor responders according to the Bologna and Poseidon criteria
Diversity for evolution
P. Humaidan, Denmark
15.40 L11 – LH in advanced maternal age and hypo-responders
Exploring new paths in the wood
A. Conforti, Italy
16.00 Revisiting poll questions day 1
Discussion
16.30 End of the first day
Session V
LH before, during and after COS: the cycle of soil cultivation
Chairs: K. Buhler, Germany; A. La Marca, Italy
09.00 Wrap-up from day 1
Poll questions day 2
09.10 L12 – Androgens priming before COS
The care in preparing furrows
N. Polyzos, Spain
09.30 L13 – LH across COSs: The Duo-Stim
The art of nourishing the soil
J. A. García Velasco, Spain
09.50 L14 – LH for ovulation triggering
The good harvest
R. Orvieto, Israel
10.10 L15 – LH activity for luteal phase support
Towards the final storage
P. Humaidan, Denmark
10.30 Discussion
11.10 Coffee break
Session VI
LH beyond the “frozen” concepts
Chairs: C. Alviggi, Italy – S. C. Esteves, Brazil
11.30 L16 – New insights into the anti-apoptotic activity of LH
Defending life in the world of ice
L. Casarini, Italy
11.50 L17 – LH in fertility preservation
A new way to prevent melting of glaciers
F. G. Klinger, Italy
12.10 L18 – Extra gonadal activity of LH
What’s below the tip of the iceberg?
R. Rizzo, Italy
12.30 Revisiting poll questions day 2
Discussion
12.55 Concluding remarks
13.00 End of the Conference and closing lunch
General Information
Partnership
This program is designed in partnership with:
Archipelagos Institute of Marine Conservation
Italian Society of Embryology, Reproduction and Research (SIERR)
Italian Society of Fertility and Sterility (SIFES)
Italian Society of Gynecology and Obstetrics (SIGO Federation)
The Portuguese Society of Reproductive Medicine (SPMR)

CME Provider
Med.E.A – Medical Education Academy