Virtual World Preceptorship on Luteinizing Hormone in ART
2 July - 30 November 2021
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Overview

The role of luteinizing hormone (LH) during folliculogenesis has intrigued the scientific and medical community for at least three decades. There is an emerging galaxy of research to explore concerning this enigmatic subject. The availability of recombinant drugs now offers, for the first time, the opportunity to examine the role of follicle stimulating hormone and LH separately. An emerging topic during last year’s conference was LH supplementation to improve the outcome in a subgroup of low prognosis patients selected according to POSEIDON classification.

This new virtual preceptorship is designed to explore the role of luteinizing activity during folliculogenesis and beyond. The virtual preceptorship will feature and summarise educational material released during the last edition of the Virtual World Conference on Luteinizing Hormone in ART. In addition, three live sessions (practical session in three ‘host’ clinics) will be streamed live and each session will provide the opportunity for more practical in-depth learning. Each live session will engage a group of participants that has prepared case studies and questions. The chairs will present selected case studies/questions focusing on LH and ART, and discuss them live together with the host Clinic team. Prior to each live session, relevant MCQ and literature will be shared with participants. The pre-live exercises will guide discussion on the optimal clinical management for each case.

During the preceptorship, the participant can also visit the chat room to discuss interesting topics and debate with colleagues. The virtual preceptorship doesn’t stop there – A library with a collection of recent articles related to the program will be freely available to all participants. We hope you find this learning experience, on the role of luteinizing hormone in ART, to benefit your on-going education. We look forward to welcoming you to this next exploration.

Learning Objectives

  • Understand the importance of luteinizing activity during folliculogenesis and beyond.
  • Understand the dynamics of hypothalamic-pituitary axis in the pathogenesis of hypo- and normo-gonadotropic amenorrhea.
  • Comprehend the concept of relative gonadotropin deficiency.
  • Discuss and debate the management of low prognosis patients.
  • Comprehend the clinical utility of the POSEIDON classification for the management of low prognosis women.
  • Discover the clinical relevance of LH supplementation in ART.
  • Appreciate the clinical relevance and pathogenesis of the progesterone rise during COS.
  • Analyse the relevance of LH during the luteal phase and Introduce the concept of individualized luteal phase support.
  • Explore the potential of LH in male infertility.

Target Audience

The programme is intended for clinicians, embryologists, andrologists, scientists, and managers working in ART who wish to update their knowledge of advanced techniques and scientific innovations and understand best practices using evidence-based models of care.

Accreditation

The live sessions has been submitted for CME accreditation to EACCME® (European Accreditation Council for Continuing for Medical Education

Language

The official language of the activity is English. Simultaneous translation (from/to English/Chinese/French/Spanish) has been provided.

Educational Format

The virtual preceptorship will feature:

6 Video lectures

that were released throughout the last Virtual World Conference on Luteinizing Hormone in ART: A New Galaxy is Born! In 2020.

6 Scribing Mapping

Of the video lectures that were released throughout the last Virtual World Conference on Luteinizing Hormone in ART: A New Galaxy is Born!

3 live sessions

(practical session) will be streamed live and each session will provide the opportunity for more practical in-depth learning.

Chat room

to discuss interesting topics and debate with colleagues.

Diploma signed by the Chair

and certificate for attending the three live sessions.

library

with a collection of articles related to the program will be provided.

Chairs

Carlo Alviggi

Naples, Italy
Biography

Robert Fisher

Hamburg, Germany
Biography

Sandro Esteves

Campinas, Brazil
Biography

Peter Humaidan

Aarhus, Denmark
Biography

Co-Chairs

Budi Wiweko

Universitas Indonesia Pondok Indah Hospital IVF Clinic Jakarta, Indonesia
Biography

Hakan Yarali

Hacettepe University Anatolia IVF and Women’s Health Center Ankara, Turkey
Biography

Faculty

Federico II University
Naples, Italy

Federico II University
Naples, Italy

Federico II University
Naples, Italy

Androfert – Andrology and Human Reproduction Clinic
Campinas, Brazil

Fertility Centre Hamburg
Hamburg, Germany

Fertility Clinic, Skive Regional Hospital
Faculty of Health, Aarhus University
Aarhus, Denmark

Laboratory Director
Anatolia IVF and Women’s Health Centre
Ankara, Turkey

Obstetrics and Gynecology
Anatolia IVF and Women’s Health Centre
Ankara, Turkey

Pondok Indah Hospital IVF Clinic
Jakarta, Indonesia

Federico II University
Naples, Italy

Pondok Indah Hospital IVF Clinic
Jakarta, Indonesia

Universitas Indonesia
Pondok Indah Hospital IVF Clinic
Jakarta, Indonesia

Hacettepe University
Anatolia IVF and Women’s Health Center
Ankara, Turkey

RS Pondok Indah IVF Center
Jakarta, Indonesia

Preliminary Programme

Download PDF

Agenda

Live Session Videos

Video Lectures

Presentation
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Presentation
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Presentation
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Presentation

General Information

Partnership

This program is designed in partnership with:

University of Naples, Federico II

Pondok Indah Hospital IVF Clinic – Jakarta, Indonesia

Anatolia IVF and Women’s Health Center – Ankara, Turkey

ASPIRE, the Asia Pacific Initiative on Reproduction

TSRM, the Turkish Reproductive Health Association

CME Provider

Med.E.A – Medical Education Academy

Chloé Xilinas, Programme and Relations Manager
in Medical Education

chloe.xilinas@medeaacademy.com

Funding

Med.E.A Srl educational programs are organized solely to promote the exchange and dissemination of scientific and medical information. No forms of promotional activities are permitted. There may be presentations discussing investigational uses of various products.
These views are the responsibility of the named speakers and do not represent an endorsement or recommendation on the part of Med.E.A. Srl. Our educational activities are supported by independent grants from the Healthcare business of Merck KGaA, Darmstadt, Germany; FUJIFILM EUROPE GMBH, Fujifilm Italia S.p.A., FUJIFILM France S.A.S., Androfert Andrology & Human Reproduction Clinic; MVZ Fertility Center Hamburg GmbH; University of North Carolina at Chapel Hill; Reproductive Medicine Agency (Nova Clinic)

· Carlo Alviggi ·

Carlo Alviggi earned his MD degree in 1994, from the Faculty of Medicine of the University of Naples “Federico II” in Naples, Italy; he specialized in obstetrics and gynaecology in 1998, and gained a PhD in 2001, from the same university. During his career, he collaborated with: The Imperial College of London, in London, UK; the Laboratory of Immunology of the Italian National Research Council in Naples; and the Autoimmunity and Tolerance Laboratory of the University of California in Los Angeles, CA, USA. This network resulted in various publications, some of which concern new hypotheses on the pathogenesis of pelvic endometriosis. He is now an associate professor in reproductive medicine at the Fertility Unit of the University of Naples “Federico II”. Professor Alviggi’s current research interests are the role of luteinizing hormone (LH) in folliculogenesis; the use of LH-containing drugs in patients undergoing ovarian controlled stimulation for IVF; the pathogenesis of pelvic endometriosis; oncofertility; reproductive endicrinology and the genetics of human reproduction. He has participated in several national and international (phase 2 and 3) multicentric, prospective randomized trials. Professor Alviggi has published extensively and has been invited to lecture at over 200 international meetings dealing with reproductive medicine and gynaecological endocrinology; he is also starter and co-founder of the Poseidon group, an international collaborative network dedicated to low prognosis patients in Assisted Reproductive Technology and vice-President of the “Società Italiana di Fertilità e Sterilità – Medicina della Riproduzione”.

· Robert Fischer ·

Robert Fischer is the founder and Medical Director of the Fertility Center Hamburg (FCH) in Hamburg, Germany. Dr Fischer trained in obstetrics and gynaecology at the University Hospital of Münster, Germany, from 1979 to 1982 and at the Queen’s Medical Centre, University of Nottingham, UK. In 1983, Dr Fischer pioneered the first German outpatient IVF unit in Hamburg and became its Medical Director. The unit moved to a new location in 1998, and its name was changed to the “Fertility Center Hamburg”.

In July 1998, the Fertility Center Hamburg was one of the first centres, both in Germany and worldwide, to introduce quality management, and it was certified according to the ISO 9001 and accredited for IVF laboratories (ISO 17025). Dr Fischer’s main research interests are in the development of stimulation protocols, luteinizing hormone supplementation, and gonadotropin-releasing hormone agonist triggering, as well as further development of quality management systems in IVF centres. He is a founding member of the European Society of Human Reproduction and Embryology (ESHRE); a founding member of the POSEIDON (Patient Oriented Strategies Encompassing IndividualizeD Oocyte Number) group);  Member of the  Scientific Committee of Excellence in Medical Education (EXCEMED- formerly the Serono Symposia International Foundation) and Scientific director of  Med.E.A.( Medical Education Academy)

· Sandro C. Esteves ·

Sandro C. Esteves, MD., PhD. is a reproductive urologist who specializes in treating male infertility, particularly its connection with assisted reproductive technology (ART). He is the founder and medical director of ANDROFERT, a fertility center based in Campinas, Brazil, dedicated to male reproductive health. He is also a Collaborating Professor of Urology at the University of Campinas (UNICAMP), Brazil, and an Honorary Professor of Reproductive Medicine at Aarhus University, Denmark.

Dr. Esteves earned his medical degree in 1990 from the Faculty of Medical Sciences at UNICAMP, where he also completed his urology residency. He pursued a research fellowship at the Cleveland Clinic Foundation in the United States, focusing on male infertility. He later obtained a master’s degree in Surgery from UNICAMP and a PhD in Urology from the Federal University of São Paulo (EPM–UNIFESP). With more than 25 years of experience, Dr. Esteves has significantly advanced our understanding of male infertility in both clinical and academic settings. His work has focused on sperm DNA fragmentation, the importance of accurate semen analysis, and the limitations of basic diagnostics. He has underscored the role of varicocele repair and hormonal therapy in improving male fertility, particularly in non-obstructive azoospermia. He is the lead author of the APHRODITE criteria, a novel classification system designed to guide the treatment of men with testicular dysfunction and improve fertility outcomes through personalized hormonal therapy.

Dr. Esteves is a prolific author with over 350 published scientific papers, as well as numerous book chapters, and textbooks. He holds a Hirsch index of 78 and has been cited over 20,ooo times. According to the Science-Wide Author Databases of Standard Citation Indicators (Elsevier/Stanford), he is ranked among the top 1% of global researchers. He is a founding member of the POSEIDON group, which developed new stratification criteria for couples with a low prognosis undergoing ART. In addition to his clinical work and research, Dr. Esteves serves as Associate Editor/Section Editor for several journals, including Human Reproduction, Andrology, Reproductive Biomedicine Online, Frontiers in Endocrinology, and the International Brazilian Journal of Urology. He is also an editorial board member of many journals, including Nature Reviews Urology and International Urology and Nephrology. At ANDROFERT, Dr. Esteves has led initiatives to implement cleanroom technologies and quality management systems (ISO 9001), achieving national recognition for excellence in male fertility care. His team has consistently delivered outstanding results in treating complex cases of male infertility. A frequent speaker at national and international conferences, Dr. Esteves has received numerous research grants and awards. He serves as the head of the Andrology Committee at the Brazilian Society of Human Reproduction and is the Topic Leader of the Male Infertility Group for the WHO Infertility Guidelines.

· Peter Humaidan ·

Professor Peter Humaidan is a specialist in reproductive endocrinology, professor at The Fertility Clinic Skive Regional Hospital, Aarhus University, Denmark and Honorary professor at Odense University, Denmark. During his scientific work he has primarily focused on developing individualized treatment protocols for the infertile patient. His doctoral thesis (DMSc) explored the role of LH during the follicular and luteal phases in controlled ovarian stimulation. His main fields of interest are triggering of ovulation with GnRH agonist, role of LH during the follicular and luteal phases, role of the female genital tract microbiota for reproductive outcomes, OHSS prevention, and role of sperm DNA fragmentation for spontaneous and assisted reproduction. He is the founder of the international society “The Copenhagen GnRHa Triggering Workshop Group” who introduced the GnRHa trigger in modern IVF, changing trigger policies worldwide. He is co-founder of the POSEIDON group which suggested a new stratification of the poor responder patient, and a past board member of the ESHRE SIG Endocrinology Group. Finally, he is also co-founder of the APHRODITE group which suggested a new classification of the infertile male into five sub-groups who might benefit from medical treatment in terms of spermatogenesis. He is in the Elsevier, Stanford global list of 2% top scientists, and he authored and co-authored 270 + articles (H-index 70, Google Scholar) in international peer reviewed journals as well as chapters in textbooks and the Danish guidelines for OHSS prevention. Peter Humaidan has a wide international scientific network and is frequently invited as a speaker at international conferences.

· Hakan Yarali ·

Professor Hakan Yaralı, MD, is the founder and Clinical Director of Anatolia IVF Center, Ankara, Turkey, one of the busiest private IVF centers in Turkey.  Following medical school and residency training in OB/GYN at Hacettepe University, he did his clinical fellowship at University of British Columbia, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, Vancouver, Canada during 1991-1992.

His special interests are clinical IVF-all aspects, in particular, luteal phase in both fresh and frozen embryo transfer cycles and management of low-prognosis patients. Dr. Yaralı has published over 130+ original articles, 80+ abstracts, 7 book chapters and delivered 80+ lectures worldwide. He has received several national and international awards, including his recognition by Human Reproduction to have produced the top contributing article to Human Reproduction’s 2014 impact factor. Anatolia IVF is currently a part of several ongoing multi-nation and multi-center collaborative projects. Professor Yaralı and his team have been organizing several preceptorship programs, training clinicians and embryologists from diverse countries. Dr. Yaralı was the former president of Turkish Society of Reproductive Medicine (TSRM).

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