Continuing Medical Education (CME)
International Workshop

How to master gonadotrophins in folliculogenesis:

LH-FSH adjustment to optimize ovarian response

27 September 2024
Modena, Italy

With the support of the University of Modena e Reggio Emilia

Overview

Folliculogenesis, the process of producing a fertilizable oocyte, has been explored and studied extensively in the past few decades. Although processes regulating the early stages of follicular development are key determinants to optimize oocyte yield, they are less explored and discussed. Therefore, there are no optimized and definitive therapies for overcoming the suboptimal ovarian response. This meeting is focused on factors/mechanisms affecting the early stages of folliculogenesis. These include the potential effects of follicle-stimulating hormone (FSH), luteinizing hormone (LH), sex steroids, anti-Müllerian hormone (AMH), and intraovarian signaling pathways on the early stages of follicle development. Discussing the latest discoveries in this field may eventually lead to improvements in Medically Assisted Reproduction (MAR) treatment for patients with ovarian-related infertility.

Learning Objectives

Objective of the event: (1) Application of the principles and procedures of Evidence Based Practice in daily practice (EBM-EBN-EBP)

After participating in this workshop and related activities, participants will be able to:

Target Audience

Clinicians working in MAR globally. As materials will be online for 12 months following the workshops, participants from other regions and different healthcare disciplines can view these activities.

Health care specialists working in ART and in infertility treatment development, particularly Academic scholars/researchers, clinicians, andrologists, embryologists, other scientists, managers, and specialist nurses who want to remain up-to-date about advanced techniques, scientific innovations, and best practices using evidence-based models of care delivery.

Language

The official language of all our educational activities is English.

European Accreditation Council for Continuing Medical Education Accreditation

“The International Workshop – How To Master Gonadotrophins In Folliculogenesis: LH – FSH adjustment to optimize ovarian response, hybrid event, Italy 27/09/2024 – 27/09/2024, has been accredited by the European Accreditation Council for Continuing Medical Education (EACCME®) with 5.5 European CME credits (ECMEC®s). Each medical specialist should claim only those hours of credit that he/she actually spent in the educational activity.”
“Through an agreement between the Union Européenne des Médecins Spécialistes and the American Medical Association, physicians may convert EACCME® credits to an equivalent number of AMA PRA Category 1 CreditsTM. Information on the process to convert EACCME® credit to AMA credit can be found here.

“Live educational activities, occurring outside of Canada, recognised by the UEMS-EACCME® for ECMEC®s are deemed to be Accredited Group Learning Activities (Section 1) as defined by the Maintenance of Certification Program of the Royal College of Physicians and Surgeons of Canada.”
Information regarding the conversion of EACCME® credits Credit will be converted based on one (1) hour of participation equalling one credit for all activities. Physicians wishing to convert EACCME® credits to AMA PRA Category 1 Credit™ will be required to access the AMA website at to obtain the necessary paperwork and instructions. Physicians and other health care professionals will be required to pay a processing fee to the AMA.

For other countries, please contact the relevant national/regional accreditation authority.

uems-eaccme-logo

Italian Ministry of Health Accreditation

This programme has been submitted for CME accreditation from the Italian Ministry of Health.

Event no.: 421486 Ed. 1

Crediti ECM: 6

This CME event is subject to AIFA filing pursuant to and for the purposes of art. 124 of D.L. 219/06

Scientific Secretariat

MedEA Medical Education Academy

chloe.xilinas@medeaacademy.com

+ 39 3466277262

Via Monte Napoleone, 8 – 20121 Milan, Italy

medeaacademy.com

ECM Provider

Event Planet Group – Id n. 3255

Tel. 342 140 5690

Federica Barletta

ecm@eventplanetgroup.com

Organising Secretariat

Event Planet Group

Marta Pani, Project Manager

marta.pani@eventplanetgroup.com

Registration Fees

STANDARD FEE – € 200,00 (+22% VAT)

REDUCED FEE – Members of medical societies* – €140,00 (+22%VAT)

REDUCED FEE – Low-income countries – €60,00 (+22%VAT)

FREE REGISTRATION FEE – Residents and fellows and training

Registration fees include

• Accreditation by the European Accreditation Council for Continuing Medical Education (EACCME®)
• Accreditation by the Italian Ministry of Health (Italian HCP)
• Access to all scientific sessions
• Certificate of attendance
• Welcome letter, Conference kit, name badge, scientific program (QR Code)
• Coffee breaks
• Lunch Break

Med.E.A. is in partnership with*

International Workshop
How to master gonadotrophins in folliculogenesis:

LH – FSH adjustment to optimize ovarian response

27 September 2024

Chairs

Livio Casarini

Livio Casarini

University of Modena and Reggio Emilia (UNIMORE)
Modena, Italy
Antonio La Marca

Antonio La Marca

University of Modena and Reggio Emilia (UNIMORE)
Modena, Italy

Faculty

Carlo Alviggi

Carlo Alviggi

Fertility Unit, University of Naples “Federico II”
Naples, Italy
Baris Ata

Baris Ata

ART Fertility Center
Koc University Istanbul
Dubai, United Arab Emirates
Livio Casarini

Livio Casarini

University of Modena and Reggio Emilia (UNIMORE)
Modena, Italy
Nathalie Di Clemente

Nathalie Di Clemente

Sorbonne Université INSERM
Centre de Recherche Saint-Antoine (CRSA)
Institut Hospitalo-Universitaire ICAN
Paris, France
Francesca Gioia Klinger

Francesca Gioia Klinger

Saint Camillus International University Of Health Science
Rome, Italy
Renato Fanchin

Renato Fanchin

University of Paris — XI
Antoine Béclère Hospital in Clamart
Clamart, France
Stine Gry Kristensen

Stine Gry Kristensen

Copenhagen University Hospital
Copenhagen, Denmark
Antonio La Marca

Antonio La Marca

University of Modena and Reggio Emilia (UNIMORE)
Modena, Italy

International Committee

Baris Ata

Baris Ata

ART Fertility Center
Koc University Istanbul
Dubai, United Arab Emirates
Alvaro Ceschin

Alvaro Ceschin

President of Brazilian Association of Assisted Reproduction (SBRA)
Brasilia, Brazil
Adriano Fregonesi

Adriano Fregonesi

Associate Professor Urology of State University of Campinas Brazil (UNICAMP) and Jundiai School of Medicine
Head of the Department of Urology / Andrology State University of Campinas Brazil
Delegate Sociedade Brasileira de Urologia São Paulo (SBU SP)
Joaquin Llácer

Joaquin Llácer

Ginefiv-GeneraLife
Madrid, Spain
Kevin McEleny

Kevin McEleny

Queen Elizabeth Hospital
Gateshead and the Freeman Hospital
Newcastle, UK
Habib Midassi

Habib Midassi

Polyclinique Ibn Annafis
Sfax, Tunisia
Paula Navarro

Paula Navarro

Ribeirão Preto Medical School
University of Sao Paulo,
Sao Paulo, Brazil
Amina Oumeziane

Amina Oumeziane

Tiziri IVF Center
Algiers, Algeria
Emre Pabuçcu

Emre Pabuçcu

Ufuk University School of Medicine
Ankara, Turkey

Agenda

· Antonio La Marca ·

Antonio La Marca is Professor of Obstetrics and Gynecology at the Mother-Infant Department of the University of Modena and Reggio Emilia, Italy and he is the Medical Director of Clinica Eugin, Modena, Italy. He graduated in Medicine and Surgery at the University of Siena in 1996, specializing in Obstetrics and Gynaecology at the same institution in 2001. In 2006 he obtained a PhD, again at the University of Siena. He has been working at the Institute of Gynaecology and Obstetrics of the University Hospital of Modena since 2003. His clinical activity covers all the field of Reproductive Medicine and Surgery and has taken part in thousands of IVF cycles, laparoscopic and hysteroscopic surgical procedures. Present scientific interests include: ovarian reserve and pharmacological manipulation of ovarian activity. His most impactful articles concerned the physiological significance of AMH and AFC, their measurement and clinical utility. Moreover, he has published a long list of original articles dealing with the prediction of ovarian reserve and response in IVF and the personalization of ovarian stimulation protocols. He is author or coauthor of 128 articles published in peerreviewed journals and authored many 26 Antonio La Marca University of Modena and Reggio Emilia and Clinica Eugin Modena, Italy chapters in national and international textbooks. He has been an Invited speaker in more than 100 international congresses. He is involved in several phase three and four trials as Principal Investigator and is the recipient of many competitively assigned research funds. He is an active member of many national and international professional and scientific societies and a consultant for the Italian Ministry of Health for female fertility-related issues.

· Carlo Alviggi ·

Carlo Alviggi earned his MD degree in 1994, from the Faculty of Medicine of the University of Naples “Federico II” in Naples, Italy; he specialized in obstetrics and gynaecology in 1998, and gained a PhD in 2001, from the same university. During his career, he collaborated with: The Imperial College of London, in London, UK; the Laboratory of Immunology of the Italian National Research Council in Naples; and the Autoimmunity and Tolerance Laboratory of the University of California in Los Angeles, CA, USA. This network resulted in various publications, some of which concern new hypotheses on the pathogenesis of pelvic endometriosis. He is now an associate professor in reproductive medicine at the Fertility Unit of the University of Naples “Federico II”. Professor Alviggi’s current research interests are the role of luteinizing hormone (LH) in folliculogenesis; the use of LH-containing drugs in patients undergoing ovarian controlled stimulation for IVF; the pathogenesis of pelvic endometriosis; oncofertility; reproductive endicrinology and the genetics of human reproduction. He has participated in several national and international (phase 2 and 3) multicentric, prospective randomized trials. Professor Alviggi has published extensively and has been invited to lecture at over 200 international meetings dealing with reproductive medicine and gynaecological endocrinology; he is also starter and co-founder of the Poseidon group, an international collaborative network dedicated to low prognosis patients in Assisted Reproductive Technology and vice-President of the “Società Italiana di Fertilità e Sterilità – Medicina della Riproduzione”.

· Baris Ata ·

Baris Ata graduated from the Istanbul School of Medicine in 1998. He completed residency training in Obstetrics and Gynecology in 2003. During medical school and residency training he attended courses on research methodology, assisted reproduction and gynecological endoscopy around the world. His keen interest to improve his research skills led to acquisition of a Master’s Degree in Clinical Trials from the prestigious London School of Hygiene and of Tropical Medicine. He completed a three years long clinical and research fellowship program in Reproductive Gynecological Endocrinology and Infertility at McGill University, Montreal, Canada in 2011. Upon returning to Turkey he founded and assumed the directorship of the assisted reproduction unit of the Uludağ University, a highly successful program that grew to over 500 IVF cycles per annum in less than two years. He recently moved to Koç University. He has several awards of excellence as a resident, fellow, clinician and scholar. His research is on clinical aspects of female infertility including but not limited to ultrasound imaging of female reproductive tract, luteal phase physiology and support, prevention and management of ovarian hyperstimulation syndrome and in vitro maturation. Baris has over 100 publications on various aspects of assisted reproduction. He is sitting on the editorial board of six journals including Human Reproduction, and is a regular ad hoc reviewer for leading journals in his field. He is a member of the executive board of the Turkish Society of Reproductive Medicine and the board of directors of the International Society of In Vitro Fertilization.

· Renato Fanchin ·

Renato Fanchin is specialized in obstetrics and gynaecology and reproductive medicine, having focused his academic and clinical activities on reproductive medicine for almost 30 years. Professor Fanchin received his PhD from the University of Paris — XI in Orsay, France, in 2005 and led the Center for Reproductive Medicine at Antoine Béclère Hospital in Clamart, France, from 2002 to 2016. Between 2016 and 2018, he then managed the Center of Reproductive Medicine at Hospital Foch in Suresnes, France. Professor Fanchin’s current research interests include the assessment of ovarian follicular status, ovarian aging, and controlled ovarian hyperstimulation strategies. He has been invited to speak at more than 250 international meetings, is a member of the Society for Gynecologic Investigation (SGI), and was awarded the Society for Assisted Reproductive Technology (SART) Prize Paper by the American Society for Reproductive Medicine (ASRM) in 1999. In collaboration with colleagues, Professor Fanchin has published almost 200 peer-reviewed articles in international journals.

· Alvaro Ceschin ·

Graduated in Medicine from the Federal University of Paraná (UFPR), in 1985.

Training in Human Reproduction at the Huntington Reproductive Center in Pasadena, California/USA, in 1991.

PhD in Principles of Surgery, in the area of concentration in Molecular Biology, from UFPR, completed in 2006, with the theme: “Comparative study of the viability of ovaries cryopreserved by slow freezing and vitrification – study in rats”.

Residency in Gynecology and Obstetrics at the Santa Brígida Hospital and Maternity Hospital, in Curitiba/PR, from 1987 to 1989.

Master’s degree in Principles of Surgery from the Research Institute of Faculdade Evangéilca do Paraná in 2002, with the theme: “Indirect hormonal assessment and study of follicular preservation in autologous ovarian tissue transplanted to the inguinal region, in rats”.

· Adriano Fregonesi ·

Free professor at the surgery department at UNICAMP. Assistant to the urology discipline at UNICAMP. Coordinator of the andrology sector of the urology discipline at UNICAMP.

· Joaquín Llacer ·

Dr. Llácer has over 30 years of experience in the field of assisted reproduction. He holds a Degree in Medicine and Surgery from the University of Valencia, specializing in obstetrics and gynecology at Hospital Universitario La Fe (Valencia) and holds a PhD in Medicine from the University Miguel Hernández of Elche. During the past 26 years Dr. Llácer has been part of the team of gynecologists at Instituto Bernabéu, where he also took part in the medical direction of the group and was a member of the Board of Directors.   

Among his professional achievements it was particularly noteworthy the extraordinary doctorate award for his thesis, as well has being awarded by the British Fertility Society and the American Society for Reproductive Medicine. In addition, Dr. Llácer has combined his medical activity with academic teaching in different master’s degree at University Complutense of Madrid and University of Alicante. He has authored over 50 papers in reproductive medicine journals, both national and international, and is currently a member of the scientific committee of the Spanish Fertility Society (SEF).

· Kevin McEleny ·

Mr Kevin McEleny is a Consultant Urologist working both in Newcastle and at the Queen Elizabeth Hospital in Gateshead since 2009.

He is also Consultant Andrologist and Clinical Lead for the male factor clinic at the Newcastle Fertility Centre, located at the International Centre for Life, Times Square, Newcastle upon Tyne.

After completing his medical training and PhD at University College, Dublin, he continued his urological training in the Northern Region prior to his consultant appointment.

His main clinical interests include treating and diagnosing men with fertility problems. He organised and delivers the supra-regional Male Fertility service.

His research interests are in the field of male fertility and he is actively involved in male fertility training nationally.

· Habib Midassi ·

Assistant professor of obstetrics and gynecology,Sfax university.Tunisia.(1987)

Mr Habib has completed his higher accreditation in Obstetrics and Gynecology in 1986

He works six years  as a consultant  in the Sfax teatching hospital .in 1988 he has his private office of gynecology and obstetrics.Since 2007 he also works in the IVF  center  of the polyclinic Ibn Annafis ,Sfax.Tunisia.

He has a wide experience in treating infertile couple with the first specialized fertility consultation in Tunisia (1984) .

Besides laparoscopic  Surgery, his professional interests include ovarian reserve ,luteal phase support and medical treatement of uterine fibroids

· Paula Andrea Navarro ·

Associate Professor at FMRP-USP (Human Reproduction Sector, Department of Gynecology and Obstetrics), President of the Scientific Integrity and Good Practices in Research Committee at FMRP-USP, Director of the Assisted Reproduction Laboratory, Deputy Coordinator of the Human Reproduction Center , Coordinator of the Postgraduate Program in Gynecology and Obstetrics at FMRP-USP, President of the Brazilian Society of Human Reproduction (SBRH, biennium 2023 to 2025), Member of the Technical Chamber of Assisted Reproduction of the Federal Council of Medicine and Member of the National Commission Specialist (CNE) of Assisted Reproduction of the Brazilian Federation of Gynecology and Obstetrics (FEBRASGO). Researcher at the National Institute of Sciences and Technology/CNPq – Hormones and Women’s Health, Ad Hoc consultant for FAPESP, CNPq and CAPES. Chief Editor of the Human Reproduction Archives, Associate Editor of Reproductive Sciences and the Brazilian Journal of Ginecology and Obstetrics, Member of the Editorial Board of the Journal of Assisted Reproduction and Genetics and Ad Hoc reviewer for several high-impact scientific journals. Graduated in Medicine from the Faculty of Medicine of Ribeirão Preto at the University of São Paulo (FMRP-USP; 1995), medical residency in Gynecology and Obstetrics at the Hospital das Clínicas de Ribeirão Preto (HCRP-USP; 1999); master’s degree (2000), Research Fellow in Reproductive Endocrinology and Infertility, Women and Infants Hospital, Brown University and Laboratory for Reproductive Medicine, Marine Biological Laboratory (2001-2002) and PhD (2003) in Health Sciences, Gynecology and Obstetrics, FMRP -USP. Post-doctorate at New York University (2016-2017). His main research interests include: Understanding the etiopathogenic mechanisms of endometriosis-related infertility and other infertility factors; Improving the efficiency of assisted reproduction techniques; Evaluate the efficiency and safety of new strategies (adds on) in assisted reproduction procedures; Improvement of fertility preservation strategies, especially oocyte freezing; Improving access to infertility treatment

· Amina Oumeziane ·

Dr Oumeziane has a Medical Degree from Medicine’s Faculty, Algiers in 1989 and Post Graduate Degree-Specialty in gynecology obstetrics from medicine’s faculty, Algiers in 1994.
Completed her training in reproductive medicine at Cochin hospital Assistance Publique Hôpitaux , Paris.
In 2000, received Academic Diploma of Investigation and Management of Infertility from Medicine’s Faculty Rene Descartes Paris, France in 2007 and Diploma in Basic of Reproductive Medicine and Embryology from International School of Medicine Kiel, Munich in 2012.
Head of Tiziri ivf center in Algiers since 2004.
Founder of of subspeciality certificate in infertility in 2019.
Amina Oumeziane is the founder of the Algerian Society of Reproductive Medicine (SAMERE), served as its First president from 2013 to 2016 and Scientific Director from 2016-until now.

Member of the American Society of Reproductive Medicine (ASRM) and European Society of Human reproduction and Embryology (ESHRE), Reviewer in global reproductive health IFFS journal, RBMO and MEFS journals Amina’s major interest areas: Luteal phase, Agonist triggering, Frozen strategy, poor responders .

· Emre Pabuçcu ·

Emre Göksan Pabuçcu was born in Ankara in 1981. After graduating from TED Ankara Private High School, he started his medical education in Ankara University Faculty of Medicine. He completed his residency program in the Department of Obstetrics and Gynecology, Ankara University Faculty of Medicine. He has been working at Ufuk University, Department of Obstetrics and Gynecology since 2013 where he received his Associated Professorship in 2017. He has worked at Houston Fertility Specialists Clinic and Texas Woman’s Hospital, Texas (2016) as an observer in the field of preimplantation genetic testing and minimal invasive surgery. He has also been working at Centrum Clinic Private IVF Center, Ankara/Turkey since 2012. He is actively interested in Reproductive Endocrinology and Reproductive Endoscopic procedures.  He is a former board member of International Society of Gynecologic Endoscopy (ISGE). Dr. Pabuçcu is currently a reviewer of several local and international journals about Reproductive Medicine, Endocrinology and Endoscopy. He has published more than 70 papers in peer reviewed journals. 

· Martin O. Savage ·

Martin Savage is Emeritus Professor of Paediatric Endocrinology at William Harvey Research Institute, Barts and the London School of Medicine & Dentistry, Queen Mary, University of London. He was head of the Paediatric Endocrine Unit at Barts and the London School of Medicine from 1982 to 2007. He has interests in growth disorders, specifically those with abnormalities in the GH-IGF-1 axis and in phenotype-genotype relationships of GH-IGF-1 axis defects, notably GH resistance. He published the first human case of an IGF-1 gene defect in the New England Journal of Medicine in 1996.  His other interests are Cushing’s syndrome and growth in chronic inflammatory diseases. He was General Secretary of the European Society for Paediatric Endocrinology (ESPE) from 1997 to 2004. He has lectured in 60 countries and has published 482 original articles, reviews, textbook chapters and books. In 2007, he was awarded the ESPE Andrea Prader Prize for contributions to paediatric endocrinology and in 2018 he received a Visionary Award from the American Human Growth Foundation. In 2022, he received a Research Excellence Award from the Dr Sulaiman Al Habib Medical Journal in Riyadh, and the British Society of Paediatric Endocrinology & Diabetes James M. Tanner Lifetime Achievement Award. He continues to lecture nationally and internationally.